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姓名：曹晓燕 |
职称/职务：教授 |
电话： |
传真： |
电子信箱：caoxiaoyan@snnu.edu.cn |
研究方向：中药材规范化栽培、药用植物快速繁育、药用植物次生代谢调控机理 |
办公地点：格物楼3404 |
一、个人简介
曹晓燕，女，教授，博士生导师，1975年11月出生。
1998年本科毕业于河南师范老员工物系，获生物技术专业学士学位；
2002年研究生毕业于陕西师范老员工命科学学院，获植物学专业硕士学位， 留校工作至今；
2010年于bevictor伟德官网获植物学专业博士学位；
2012.4-2013.4在美国弗吉尼亚大学从事访学研究。
主要从事中药材规范化栽培、药用植物快速繁育、药用植物次生代谢调控机理等方面的研究工作。兼任陕西省植物学会副理事长，陕西省植物学会药用植物专业委员会主任委员。
先后主持国家级和省部级科研项目十余项，包括国家自然科学基金2项、国家“十一五”科技支撑计划1项、国家“十二五”科技支撑计划子课题1项，国家“十三五”重点研发计划项目子课题1项，陕西省重点研发计划项目2项，在<J Agr Food Chem>，<Plant Sci>，<Int J Mol Sci>，<中国科学>等国内外刊物上发表论文80余篇，主编、参编教材2部，参与选育中药材新品种2个；2019年作为团队带头人申请的“秦岭道地药材保护与繁育研究创新团队”获批陕西高校青年创新团队建设项目；获得2017年陕西省高等学校科学技术奖一等奖1项，2022年陕西省教学成果一等奖1项。
二、主要研究领域及兴趣
中药材规范化栽培
药用植物快速繁育
药用植物次生代谢调控机理
三、代表性论文
1.Zhang Y, Zhang T, Pan Y, Ma L, Fang Y, Pan C, Qiang Y,Cao X*, Xu H*, Nano-selenium promotes the product quality and plant defense of Salvia miltiorrhiza by inducing tanshinones and salvianolic acids accumulation.Industrial Crops and Products, 2023, 195:116436.
2.Yang R, Li S, Dong S, Wang L, Qin H, Zhan H, Wang D,Cao X*, Xu H*. SmJAZ4 interacts with SmMYB111 or SmMYC2 to inhibit the synthesis of phenolic acids in Salvia miltiorrhiza.Plant Sci. 2023, 327:111565.
3.Wang SS, Zhang T, Wang L, Dong S, Wang DH, Li B,Cao XY*. Thedynamic changes in the main substances in Codonopsis pilosula root provide insights into the carbon flux between primary and secondary metabolism during different growth stages.Metabolites. 2023,13(3):456.
4.Zhang T, Zhang YH, Yang JX, Wang XZ, Yang QQ, Zhu XJ,Cao XY*.Transcriptome and targeted metabolome analysis revealed the effects of combined red and blue light on the growth and secondary metabolism of Scutellaria baicalensis Georgi.Industrial Crops & Products,2022,188:115598.
5.Wang W, Hu S, Yang J, Zhang C, Zhang T, Wang D,Cao X*, Wang Z*. A Novel R2R3-MYB Transcription Factor SbMYB12 Positively Regulates Baicalin Biosynthesis in Scutellaria baicalensis Georgi.Int J Mol Sci. 2022, 23(24):15452.
6.Yang QQ, Hua WP, Zou HL, Yang JX, Wang XZ, Zhang T, Wang DH, Zhu XJ,Cao XY*. Overexpression of SmLAC25 promotes lignin accumulation and decreases salvianolic acid content in Salvia miltiorrhiza.Plant Sci.2022, 325:111462.
7.Wang X, Cao Y, Yang J, Zhang T, Yang Q, Zhang Y, Wang D,Cao X*. Transcription Factor SmSPL2 Inhibits the Accumulation of Salvianolic Acid B and Influences Root Architecture.Int J Mol Sci. 2022, 23(21):13549.
8.Chen R, Cao Y, Wang W, Li Y, Wang D, Wang S,Cao X﹡. Transcription factor SmSPL7 promotes anthocyanin accumulation and negatively regulates phenolic acid biosynthesis inS alvia miltiorrhiza.Plant Sci. 2021, 310:110993.
9.Cao Y, Chen R, Wang WT, Wang DH﹡,Cao XY*. SmSPL6 induces phenolic acid biosynthesis and affects root development in Salvia miltiorrhiza.Int. J. Mol. Sci.2021,22, 7895
10.Yang R, Wang S, Zou H, Li L, Li Y, Wang D, Xu H*,Cao, X*. R2R3-MYB Transcription Factor SmMYB52 Positively Regulates Biosynthesis of Salvianolic Acid B and Inhibits Root Growth in Salvia miltiorrhiza.Int. J. Mol. Sci.2021,22, 9538.
11.Wang W, Hu S, Cao Y, Chen R, Wang Z,Cao X*. Selection and evaluation of reference genes for qRT-PCR of Scutellaria baicalensisGeorgi under different experimental conditions.Mol Biol Rep.2021, 48(2):1115-1126.
12.Li L, Liu Y, Huang Y, Li B, Ma W, Wang D,Cao X*, Wang Z*. Genome-wide identification of the TIFY family in Salvia miltiorrhiza reveals that SmJAZ3 interacts with SmWD40-170, a relevant protein that modulates secondary metabolism and development.Front Plant Sci.2021,12:630424.
13.Zou H, Guo X, Yang R, Wang S, Li L, Niu J, Wang D,Cao X*. MiR408-SmLAC3module participates in salvianolic acid B synthesis in Salvia miltiorrhiza.Int. J. Mol. Sci.2021,22, 7541.
14.Yang J, Guo Z, Wang W,Cao X*, Yang X*. Genome-wide characterization of SPL gene family inCodonopsis pilosulareveals the functions of CpSPL2andCpSPL10in promoting the accumulation of secondary metabolites and growth of C. pilosulahairy root.Genes2021,12, 1588.
15.Li L, Wang D, Zhou L, Yu X, Yan X, Zhang Q, Li B, Liu Y, Zhou W,Cao X*, Wang Z*. JA-Responsive Transcription Factor SmMYB97 Promotes Phenolic Acid and Tanshinone Accumulation in Salvia miltiorrhiza.J Agric Food Chem.2020, 68(50):14850-14862.
16.Peng JJ, Wu YC, Wang SQ, Niu JF*,Cao XY*. SmbHLH53 is relevant to jasmonate signaling and plays dual roles in regulating the genes for enzymes in the pathway for salvianolic acid B biosynthesis in Salvia miltiorrhiza.Gene.2020, 756:144920.
17.Yang J, Yang X, Kuang Z, Li B, Lu X,Cao X*, Kang J*. Selection of suitable reference genes for qRT-PCR expression analysis of Codonopsis pilosulaunder different experimental conditions.Mol Biol Rep.2020, 47(6):4169-4181.
18.Yang J, Yang X, Li B, Lu X, Kang J,Cao X*. Establishment of in vitro culture system for Codonopsis pilosula transgenic hairy roots.3 Biotech,2020, 10(3):137.
19.Guo Z, Kuang Z, Wang Y, Zhao Y, Tao Y, Cheng C, Yang J, Lu X, Hao C, Wang T,Cao X, Wei J, Li L*, Yang X*. PmiREN: a comprehensive encyclopedia of plant miRNAs.Nucleic Acids Res.2020, 48(D1): D1114-D1121.
20.Li S, Wu Y, Kuang J, Wang H, Du T, Huang Y, Zhang Y,Cao X*, Wang Z*. SmMYB111 is a key factor to phenolic acid biosynthesis and interacts with both SmTTG1 and SmbHLH51 inSalvia miltiorrhiza. J. Agric. Food Chem.2018, 66, 8069-8078.
21.Wu Y, Zhang Y, Li L, Guo X, Wang B,Cao X*, Wang Z*. AtPAP1 interacts with and activates SmbHLH51, a positive regulator to phenolic acids biosynthesis in Salvia miltiorrhiza.Front. Plant Sci.2018, 9: 1687.
22.Du T, Niu J, Su J, Li S, Guo X, Li L,Cao X*, Kang J*. SmbHLH37 functions antagonistically with SmMYC2 in regulating jasmonate-mediated biosynthesis of phenolic acids in Salvia miltiorrhiza.Front. Plant Sci. 2018, 9:1720.
23.Guo X, Niu J,Cao X*. Heterologous Expression of Salvia miltiorrhiza MicroRNA408 Enhances Tolerance to Salt Stress in Nicotiana benthamiana. Int J Mol Sci. 2018,19: 3985.
24.Wang B, Niu J, Li B , Huang Y, Han L, Liu Y, Zhou W, Hu S, Li L, Wang D, Wang S, Cao X*, and Wang Z*. Molecular Characterization and Overexpression of SmJMT Increases the Production of Phenolic Acids in Salvia miltiorrhiza. Int J Mol Sci. 2018,19:3788.
25.Yang N, Zhou W, Su J, Wang X, Li L, Wang L,Cao X* and Wang Z*. Overexpression of SmMYC2 increases the production of phenolic acids in Salvia miltiorrhiza.Front. Plant Sci.2017, 8:1804.
26.Wang XF, Su J, Yang Na, Zhang H,Cao XY*, KangJF*. Functional characterization of selected universal stress protein from Salvia miltiorrhiza (SmUSP) in Escherichia coli.Genes,2017, 8, 224.
